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DiscoverX corporation treespot compound profile visualization tool
Kinase specificity of SBP3. Kinase screen measuring the binding of SBP3 (at 2 μM) to 55 kinases of the CMGC branch. The circles indicate “percent of control” values (see Supporting Experimental Procedures), with red circles indicating high SBP3 binding (the circle size is proportional to binding strength) and green circles indicating low or no binding (scores >35%). The values for kinases that strongly interact with SBP3 (scores ≤35%) are listed. Values for all kinases tested are summarized in Table S2. The image was generated using the <t>TREEspot</t> compound profile visualization tool (KINOMEscan, DiscoverX).
Treespot Compound Profile Visualization Tool, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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treespot compound profile visualization tool - by Bioz Stars, 2026-07
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Kinase specificity of SBP3. Kinase screen measuring the binding of SBP3 (at 2 μM) to 55 kinases of the CMGC branch. The circles indicate “percent of control” values (see Supporting Experimental Procedures), with red circles indicating high SBP3 binding (the circle size is proportional to binding strength) and green circles indicating low or no binding (scores >35%). The values for kinases that strongly interact with SBP3 (scores ≤35%) are listed. Values for all kinases tested are summarized in Table S2. The image was generated using the TREEspot compound profile visualization tool (KINOMEscan, DiscoverX).

Journal: ACS Medicinal Chemistry Letters

Article Title: Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors

doi: 10.1021/acsmedchemlett.7b00127

Figure Lengend Snippet: Kinase specificity of SBP3. Kinase screen measuring the binding of SBP3 (at 2 μM) to 55 kinases of the CMGC branch. The circles indicate “percent of control” values (see Supporting Experimental Procedures), with red circles indicating high SBP3 binding (the circle size is proportional to binding strength) and green circles indicating low or no binding (scores >35%). The values for kinases that strongly interact with SBP3 (scores ≤35%) are listed. Values for all kinases tested are summarized in Table S2. The image was generated using the TREEspot compound profile visualization tool (KINOMEscan, DiscoverX).

Article Snippet: The image was generated using the TREEspot compound profile visualization tool (KINOMEscan, DiscoverX).

Techniques: Binding Assay, Control, Generated